5.14: Understand that Large Amounts of Human Insulin can be Manufactured from Genetically Modified Bacteria that are Grown in a Fermenter

INSULIN: Lowers Blood Glucose Levels by Turning Glucose in the Blood to Glycogen (insoluble) To be Stored in Muscles and the Liver

HOW INSULIN IS MANUFACTURED

MANUFACTURE OF INSULIN

Diagram Showing the Manufacture of Insulin

EXPLANATION: Restriction Enzyme is Used to Cut Out Insulin Gene (Gene for Making Insulin) from Human DNA Restriction Enzyme is Used to Cut Open Plasmid DNA of Bacteria Insulin Gene is Inserted into Plasmid DNA of Bacteria and is Joined Together using Ligase Enzyme Insulin Gene is Now Recombinant and Inserted into a Bacterial Cell (Vector) Transgenic Bacteria is Complete (Contains Genes from Different Species) and is Grown in a Fermenter to Reproduce and Duplicate

USES OF MANUFACTURED INSULIN: Helps those who has Diabetes as their Body Does Not Produce Enough Insulin but has High Blood Glucose Levels, so Not All Glucose is Reabsorbed Insulin can be Injected will Help Lower Blood Glucose Levels by Converting Glucose into Glycogen (Insoluble) which is Stored in the Muscles and the Liver